[ Monash University ]

Museum of Pathology

BRAIN GLIOMA, GRADE II

BRAIN GLIOMA, GRADE II

Clinical History

The patient was a female aged 24 years, who presented 1 1/2 years before death with an abnormal EEG after a single epileptic fit, and "blurred" discs. 6 months later she complained of blurred vision, headaches and bilateral papilloedema was seen on examination. There were no localising signs. Further investigation showed a brain tumour which was biopsied and diagnosed as a Grade II glioma. This was treated with radiotherapy. A month after treatment began the patient experienced weakness of the left arm and leg. Soon afterwards she was admitted with drowsiness and vomiting and died.

Pathology

The specimen shows an intracerebral lesion which has obliterated the lateral ventricle and the inner 2/3 of the internal capsule and basal ganglia on the right side, and which is infiltrating across the corpus callosum and distorting the aqueduct. The tumour is fairly well demarcated and vascular with numerous haemorrhagic parts.