The patient was a 73-year-old woman who had been well until three months prior to death. Initial symptoms were headache and slight unsteadiness. She was admitted after developing a left-sided hemiplegia. Investigations suggested an inoperable tumour and the patient died 1 week later.
A coronal section through the cerebral hemisphere demonstrates a poorly demarcated pale tumour in the right temporal lobe. There is enlargement of the hemispheres and flattening of the gryal pattern. Sub-falcine herniation is appreciated better on the posterior aspect of the specimen where the tumour also appears less well differentiated with haemorrhagic and necrotic foci. Histologically, the appearances are those of an Astrocytoma, Grade III to IV.