[ Monash University ]

Museum of Pathology

1_ LYMPHOMA OF THE THYROID

1_ LYMPHOMA OF THE THYROID

Clinical History

A 68 year old woman presented with a small hard lump in the thyroid. During the following six weeks there was progressive rapid enlargement of the mass to produce laryngeal stridor and oesophageal obstruction which were the terminal features. No lymph nodes were enlarged and there was no splenomegaly.

Pathology

The larynx, thyroid, upper trachea and oesophagus are included in the specimen. The enlarged left lobe and to a lesser degree, the right lobe of the thyroid, are replaced by homogeneous pale tumour tissue. Stretched over the lateral margin of the left lobe is the common carotid artery. Note how the larynx is compressed and the oesophagus virtually disappears into the bulk of the tumour. The histological appearance of the tumour was consistent with lymphoblastic lymphoma of the thyroid. The rarity of this tumour makes it necessary to exclude the diagnosis of anaplastic carcinoma of the thyroid, and secondary spread from lymphoma elsewhere.