A 62 year old man who presented with anaemia and splenomegaly was found to suffer from myelofibrosis. He required frequent transfusions and splenectomy was advised.
Two slices of an enlarged spleen are displayed separately, one stained to show a positive Prussian Blue reaction for iron. The spleen is dark red in colour. This is an example of haemosiderosis due to multiple blood transfusions in a patient suffering from myelofibrosis.