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Museum of Pathology

MALIGNANT LYMPHOMA - DIFFUSE LARGE CELL TYPE

MALIGNANT LYMPHOMA - DIFFUSE LARGE CELL TYPE

Clinical History

An elderly man presented with dyspnoea and enlarged cervical glands. Chest x-ray revealed a mass in the right side of the mediastinum. Later a right-sided pleural effusion developed and death followed

Pathology

The right femur has been sawn longitudinally to display the marrow cavity which is filled by greyish mottled material in the upper two thirds with some replacement of cancellous bone. Histology revealed diffuse infiltration by large atypical "histiocytic" cells, ie: in current terminology, large cell lymphoma.